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Bio

Director
Akihiko Sekizawa

Main Research Topics

出生前遺伝学的検査
妊娠高血圧症候群の発症予知と予防

Career History

1988年 4月昭和大学医学部産婦人科学講座 前期助手
1991年 5月昭和大学医学部産婦人科学講座 助手
1994年 6月国立精神・神経センター 国府台病院 産婦人科医員
1996年 7月昭和大学医学部 産婦人科学講座 助手
1997年 4月Tufts University, Tufts-New England Medical Center, Division of Genetics
Research Fellow (Prof. Diana W Bianchi)
1998年12月昭和大学医学部 産婦人科学講座 助手
2001年 4月昭和大学医学部 産婦人科学講座 講師
2007年12月昭和大学医学部 産婦人科学講座 准教授
2013年 4月昭和大学医学部 産婦人科学講座 教授(現在に至る)

Education

1988年3月昭和大学医学部卒業

Qualifications

産婦人科専門医・指導医;周産期(母体・胎児)専門医・指導医;
臨床遺伝専門医・指導医

Professional Membership

日本産科婦人科学会・日本周産期・新生児医学会・日本人類遺伝学会・日本妊娠高血圧学会など

Papers

  • Prenatal Identification of Confined Placental Mosaicism in Pregnant Women with Fetal Growth Restriction. Miyagami K, Shirato N, Izumi M, Hirose T, Yasui O, Hamada S, Matsuoka R, Suzumori N, Sekizawa A. Reprod Sci. 2021 Oct 28
  • Postpartum questionnaire survey of women who tested negative in a non-invasive prenatal testing: examining negative emotions towards the test. Hirose T, Shirato N, Izumi M, Miyagami K, Sekizawa A. J Hum Genet. 2021 Jun;66(6):579-584
  • Improved library preparation protocols for amplicon sequencing-based noninvasive fetal genotyping for RHD-positive D antigen-negative alleles. Hori A, Ogata-Kawata H, Sasaki A, Takahashi K, Taniguchi K, Migita O, Kawashima A, Okamoto A, Sekizawa A, Sago H, Takada F, Nakabayashi K, Hata K. BMC Res Notes. 2021 Sep 26;14(1):380.
  • Aortic dissection during pregnancy and puerperium: A Japanese nationwide survey. Tanaka H, Kamiya CA, Horiuchi C, Morisaki H, Tanaka K, Katsuragi S, Hayata E, Hasegawa J, Nakata M, Sekizawa A, Ishiwata I, Ikeda T. J Obstet Gynaecol Res. 2021 Apr;47(4):1265-1271.
  • Assessment of the value of measuring soluble fms-like tyrosine kinase-1 and placental growth factor levels following administration of tadalafil to treat fetal growth restriction. Tanaka H, Koide K, Nakamura M, Maki S, Takakura S, Enomoto N, Tanaka K, Katsuragi S, Sekizawa A, Ikeda T. J Matern Fetal Neonatal Med. 2021 Dec 16:1-5.
  • Retrospective details of false-positive and false-negative results in non-invasive prenatal testing for fetal trisomies 21, 18 and 13. Suzumori N, Sekizawa A, et al. Eur J Obstet Gynecol Reprod Biol. 2021 Jan;256:75-81.
  • The role of first-trimester ultrasound screening for women with positive noninvasive prenatal testing results. Saito M, Tokunaka M, Goto M, Takita H, Arakaki T, Miyagami K, Hamada S, ObaT, Matsuoka R, Sekizawa A. J Obstet Gynaecol Res. 2021 Dec 16.
  • Pregnancy-associated hemorrhagic stroke: A nationwide survey in Japan. Enomoto N, Tanaka H, Katsuragi S, Hayata E, Hasegawa J, Nakata M, Takahashi JC, Sekizawa A, Ishiwata I, Ikeda T. J Obstet Gynaecol Res. 2021 Jun;47(6):2066-2075.
  • Accuracy of the FMF Bayes theorem-based model for predicting preeclampsia at 11-13 weeks of gestation in a Japanese population. Goto M, Koide K, Tokunaka M, Takita H, Hamada S, Nakamura M, Matsuoka R, Sekizawa A, Poon LC. Hypertens Res. 2021 Jun;44(6):685-691
  • Nationwide study of mortality and survival in pregnancy-related streptococcal toxic shock syndrome. Hayata E, Nakata M, Hasegawa J, Tanaka H, Murakoshi T, Mitsuda N, Sekizawa A, Ikeda T, Ishiwata I. J Obstet Gynaecol Res. 2021 Mar;47(3):928-934
  • Clinical characteristics of pregnant women with COVID-19 in Japan: a nationwide questionnaire survey. Arakaki T, Hasegawa J, Sekizawa A, Ikeda T, Ishiwata I, Kinoshita K; Japan Association of Obstetricians and Gynecologists (JAOG). BMC Pregnancy Childbirth. 2021 Sep 18;21(1):636
  • Evaluation of the clinical performance of noninvasive prenatal testing at a Japanese laboratory. Sasaki Y, Yamada T, Sekizawa A, et al. J Obstet Gynaecol Res. 2021 Aug 5
  • Maternal Death Related to Sudden Unexpected Death in Epilepsy: A Nationwide Survey in Japan. Tanaka H, Katsuragi S, Hasegawa J, Tanaka K, Nakamura M, Hayata E, Nakata M, Sekizawa A, Ishiwata I, Ikeda T. Brain Sci. 2021 Jul 28;11(8):995
  • Infective endocarditis due to Streptococcus agalactiae in the puerperal period. Nakamura T, Seo K, Okuyama A, Ichizuka K, Sekizawa A, Nagatsuka M. J Obstet Gynaecol Res. 2021 Jun;47(6):2238-2241
  • The routine use of prophylactic Bakri balloon tamponade contributes to blood loss control in major placenta previa. Arakaki T, Matsuoka R, Takita H, Oba T, Nakamura M, Sekizawa A. Int J Gynaecol Obstet. 2021 Sep;154(3):508-514
  • Ultrasonographic study of umbilical cord twist direction during second trimester. Nakamura M, Oba T, Salafia CM, Morimoto T, Takita H, Tokunaka M, Goto M, Hamada S, Matsuoka R, Sekizawa A. J Matern Fetal Neonatal Med. 2021 Aug 6:1-7.
  • Issues of infant feeding for postnatal prevention of human T-cell leukemia/lymphoma virus type-1 mother-to-child transmission. Itabashi K, Miyazawa T, Nerome Y, Sekizawa A, Moriuchi H, Saito S, Yonemoto N. Pediatr Int. 2021 Mar;63(3):284-289.
  • Analysis of preventability of malignancy-related maternal death from the nationwide registration system of maternal deaths in Japan. Katsuragi S, Tanaka H, Hasegawa J, Kanayama N, Nakata M, Murakoshi T, Osato K, Nakamura M, Tanaka K, Sekizawa A, Ishiwata I, Yamamoto Y, Wakasa T, Takeuchi M, Yoshimatsu J, Ikeda T. J Matern Fetal Neonatal Med. 2021 Feb;34(3):432-438
  • Current status of community-acquired infection of COVID-19 in delivery facilities in Japan. Hasegawa J, Arakaki T, Sekizawa A, Ikeda T, Ishiwata I, Kinoshita K; department of medical safety, the Japan Association of Obstetricians and Gynecologists (JAOG). PLoS One. 2021 May 20;16(5):e0251434.
  • Pulmonary thromboembolism during pregnancy and puerperium: Comparison of survival and death cases. Takakura S, Tanaka H, Tanaka K, Katsuragi S, Hayata E, Nakata M, Hasegawa J, Sekizawa A, Ishiwata I, Ikeda T. J Obstet Gynaecol Res. 2021 Apr;47(4):1312-1321.
  • Recent Prevalence of Human T-cell Leukemia Virus Type 1 Carrier Associated with Horizontal Transmission in Pregnant Japanese Women. Suzuki S, Hoshi SI, Sekizawa A, Sagara Y, Kinoshita K, Kitamura T. Jpn J Infect Dis. 2021 Apr 30.
  • Study for risks of amniocentesis in anterior placenta compared to placenta of other locations. Goto M, Nakamura M, Takita H, Sekizawa A. Taiwan J Obstet Gynecol. 2021 Jul;60(4):690-694.
  • Survey on spontaneous miscarriage and induced abortion surgery safety at less than 12 weeks of gestation in Japan. Nakamura E, Kobayashi K, Sekizawa A, Kobayashi H, Takai Y; Medical Safety and Education Committee of the Japan Association of Obstetricians and Gynecologists (JAOG), Tokyo, Japan. J Obstet Gynaecol Res. 2021 Sep 27
  • Examination of clinical factors affecting intrauterine microbiota. Kei Odawara, Ryosuke Akino, Akihiko Sekizawa, Miwa Sakamoto, Seo Yuriko, Kanako Tanaka, Mutsumi Mikashima, Masami Suzuki, and Yasushi Odawara. Reproduction and Fertility, 2021 (1), 1–6

Competitive Research Funds

  • 出生前診断の提供等に係る体制の構築に関する研究 (厚労科研研究費・分担研究)
  • 出生前検査に関する妊産婦等の意識調査や支援体制構築のための研究 (厚労科研研究費・分担研究)
  • 妊娠高血圧症候群と胎児発育不全の克服を目的とした、ホスホジエステラーゼ5阻害剤タダラフィルによる新規予防法と治療法の開発(AMED-Birthday・分担研究)
  • HTLV-1母子感染対策および支援体制の課題の検討と対策に関する研究(厚労科研研究費・分担研究)
  • 産婦死亡に関する情報の管理体制の構築及び予防介入の展開に向けた研究(厚労科研研究費・分担研究)
  • 母体脂肪組織由来幹細胞を用いたダウン症胎児に対する幹細胞治療法の開発(おぎゃー献金基金・研究代表)
  • 無侵襲的胎児RHDジェノタイピング技術を遺伝学的検査として確立するための制度評価(成育医療研究費・分担研究)
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